Users getting "access denied to method" error in almost every module in AX 2012

We have custom roles setup for users. We haven’t made any changes to the roles, permissions or duties of any users.

But suddenly all the users are getting “Access denied to method” error in every module, something like shown in the image below.

Why do we get this error when we have given appropriate privileges to all the users?

1817.Access Denied Error.jpg

Are the custom roles created are assigned to user or still the default roles have been applied ?