Sales Invoice do not add up

Attain is a new term to me here in Australia, but reading the other entries in this forum I take it to be the release we know as Version 3.xx. My feeling, no real quantitative proof, is that the problem has reduced since cache was enabled ? We have only just moved from 2.01 to 2.60.E in the last few weeks and that has produced enough problems for a while. Release 3.xx is not up for consideration this year.